Pak expert develops bio-marker for early stroke diagnosis


Karachi, July 30 (PPI): A Pakistani professor at the University of Technology, Sydney, Australia has developed a bio-marker for early diagnosis of stroke

Dr. Kaneez Fatima Shad, Professor of Neuroscience, University of Technology Sydney, Australia has told academic audience that her group has developed a bio-marker for the early diagnosis of stroke.


She delivered a lecture on “Why Brain? Why Advocacy? Setting the future for Neuroscience with peripheral markers of mental disorders in Pakistan”. This lecture was organized by the Prof. Dr. Viqar Sultana, Department of Biochemistry, University of Karachi.

Dr. Fatima Shad did her Ph.D. in 1994 in Neuroscience from the University of New South Wales, Australia and postdoctoral studies from Medical College of Pennsylvania, USA. Her area of research interest is to find biological markers for brain disorders such as Alzheimer’s disease, Schizophrenia and Stroke.

She has more than 30years experience in teaching Physiology, Neurophysiology and other medical sciences in different universities of Australia, UAE, USA, Bahrain, Brunei and Pakistan. She has published 56 peer reviewed papers, edited three books and wrote three book chapters and 95 international peer reviewed conference abstract.

Many factors including stress, noise and carbon monoxide pollution are responsible for common neurological, neuropsycological and psychiatric disorders in Pakistan. She gave many examples as peripheral markers of such diseases for example generation of reactive oxygen species (ROS) as precursor of atherosclerosis leading to ischemic stroke. She advice to practice caloric restriction so their energy producing machine (mitochondria) will produce less ROS

She told that currently there is no biomarker available for the early diagnosis of stroke. Specific enzyme serine racemase in the blood can be used as a peripheral marker for neuronal hyperactivities and D-serine concentration is an important determinant for stroke. Her group in Australia has developed certain biochemical method for the early diagnosis of stroke, as to identify the people who are prone to have stroke in future. The early diagnosis will save the patients from the onset of stroke. The lecture was attended by a large number of faculty members and research students from the Faculty of Science University of Karachi.