To ensure that PrEP to produce effective prevention it must certanly be taken precisely and regularly. 66 Guys who possess intercourse with guys must be counselled and informed concerning the proper utilization of PrEP prior to it being provided. PrEP does not offer security against STIs, of course perhaps maybe not taken regularly is significantly less efficient, therefore will not change other avoidance options like condoms.
There has been issues that PrEP usage may lead to a decrease in condom usage, nonetheless these have already been refuted by studies, such as the PROUD study when you look at the UK. 67 A 2019 evidence review analysing 20 studies that are prEP studies discovered high prices of STIs among males that have intercourse with males whom use PrEP. Nonetheless, this will not indicate PrEP use is causing STI rates to increase. 68 69
A report published in 2018 points towards the known undeniable fact that STI prices among males who possess intercourse with guys have now been increasing when it comes to previous twenty years, which means that PrEP alone cannot give an explanation for enhance. Outcomes claim that there are more behavioural things to consider, such as for example alterations in blending patterns within danger teams, utilization of smartphone relationship applications, team intercourse, recreational medication usage, and use of medical. 70